RPPA-based protein profiling reveals eIF4G overexpression and 4E-BP1 serine 65 phosphorylation as molecular events that correspond with a pro-survival phenotype in chronic lymphocytic leukemia

Chronic lymphocytic leukemia (CLL), the most common adult leukemia, remains incurable despite advancements in treatment regimens over the past decade. Several expression profile studies have been pursued to better understand CLL pathogenesis. However, these large-scale studies only provide informati...

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Detalles Bibliográficos
Autores principales: Shull, Austin Y., Noonepalle, Satish K., Awan, Farrukh T., Liu, Jimei, Pei, Lirong, Bollag, Roni J., Salman, Huda, Ding, Zhiyong, Shi, Huidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546493/
https://www.ncbi.nlm.nih.gov/pubmed/25999352

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