Cargando…

Modulation of Estrogen Response Element-Driven Gene Expressions and Cellular Proliferation with Polar Directions by Designer Transcription Regulators

Estrogen receptor α (ERα), as a ligand-dependent transcription factor, mediates 17β-estradiol (E2) effects. ERα is a modular protein containing a DNA binding domain (DBD) and transcription activation domains (AD) located at the amino- and carboxyl-termini. The interaction of the E2-activated ERα dim...

Descripción completa

Detalles Bibliográficos
Autores principales: Muyan, Mesut, Güpür, Gizem, Yaşar, Pelin, Ayaz, Gamze, User, Sırma Damla, Kazan, Hasan Hüseyin, Huang, Yanfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546503/
https://www.ncbi.nlm.nih.gov/pubmed/26295471
http://dx.doi.org/10.1371/journal.pone.0136423