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Heparan Sulfate Biosynthesis Enzyme, Ext1, Contributes to Outflow Tract Development of Mouse Heart via Modulation of FGF Signaling

Glycosaminoglycans are important regulators of multiple signaling pathways. As a major constituent of the heart extracellular matrix, glycosaminoglycans are implicated in cardiac morphogenesis through interactions with different signaling morphogens. Ext1 is a glycosyltransferase responsible for hep...

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Detalles Bibliográficos
Autores principales:	Zhang, Rui, Cao, Peijuan, Yang, Zhongzhou, Wang, Zhenzhen, Wu, Jiu-Lin, Chen, Yan, Pan, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546591/ https://www.ncbi.nlm.nih.gov/pubmed/26295701 http://dx.doi.org/10.1371/journal.pone.0136518

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