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Casitas B-Lineage Lymphoma RING Domain Inhibitors Protect Mice against High-Fat Diet-Induced Obesity and Insulin Resistance

The casitas b-lineage lymphoma (c-Cbl) is an important adaptor protein with an intrinsic E3 ubiquitin ligase activity that interacts with E2 proteins such as UbCH7. c-Cbl plays a vital role in regulating receptor tyrosine kinase signaling. c-Cbl involves in whole-body energy homeostasis, which makes...

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Detalles Bibliográficos
Autores principales:	Wu, Min, Sun, Lin, Pessetto, Ziyan Yuan, Zang, Zhihe, Xie, Xingliang, Zhong, Ling, Su, Qing, Zan, Wang, Gao, Xiurong, Zhao, Yan, Sun, Yiyi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546618/ https://www.ncbi.nlm.nih.gov/pubmed/26296084 http://dx.doi.org/10.1371/journal.pone.0135916

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