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Genetic and Informatic Analyses Implicate Kif12 as a Candidate Gene within the Mpkd2 Locus That Modulates Renal Cystic Disease Severity in the Cys1(cpk) Mouse

We have previously mapped the interval on Chromosome 4 for a major polycystic kidney disease modifier (Mpkd) of the B6(Cg)-Cys1 (cpk)/J mouse model of recessive polycystic kidney disease (PKD). Informatic analyses predicted that this interval contains at least three individual renal cystic disease s...

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Detalles Bibliográficos
Autores principales:	Mrug, Michal, Zhou, Juling, Yang, Chaozhe, Aronow, Bruce J., Cui, Xiangqin, Schoeb, Trenton R., Siegal, Gene P., Yoder, Bradley K, Guay-Woodford, Lisa M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546649/ https://www.ncbi.nlm.nih.gov/pubmed/26295839 http://dx.doi.org/10.1371/journal.pone.0135678

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