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Birth Cohort, Age, and Sex Strongly Modulate Effects of Lipid Risk Alleles Identified in Genome-Wide Association Studies

Insights into genetic origin of diseases and related traits could substantially impact strategies for improving human health. The results of genome-wide association studies (GWAS) are often positioned as discoveries of unconditional risk alleles of complex health traits. We re-analyzed the associati...

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Detalles Bibliográficos
Autores principales: Kulminski, Alexander M., Culminskaya, Irina, Arbeev, Konstantin G., Arbeeva, Liubov, Ukraintseva, Svetlana V., Stallard, Eric, Wu, Deqing, Yashin, Anatoliy I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546650/
https://www.ncbi.nlm.nih.gov/pubmed/26295473
http://dx.doi.org/10.1371/journal.pone.0136319

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