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Arming of MAIT Cell Cytolytic Antimicrobial Activity Is Induced by IL-7 and Defective in HIV-1 Infection
Mucosa-associated invariant T (MAIT) cells represent a large innate-like evolutionarily conserved antimicrobial T-cell subset in humans. MAIT cells recognize microbial riboflavin metabolites from a range of microbes presented by MR1 molecules. MAIT cells are impaired in several chronic diseases incl...
Autores principales: | Leeansyah, Edwin, Svärd, Jenny, Dias, Joana, Buggert, Marcus, Nyström, Jessica, Quigley, Máire F., Moll, Markus, Sönnerborg, Anders, Nowak, Piotr, Sandberg, Johan K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546682/ https://www.ncbi.nlm.nih.gov/pubmed/26295709 http://dx.doi.org/10.1371/journal.ppat.1005072 |
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