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Mechanisms underlying 3-bromopyruvate-induced cell death in colon cancer

3-Bromopyruvate (3BP) is an energy-depleting drug that inhibits Hexokinase II activity by alkylation during glycolysis, thereby suppressing the production of ATP and inducing cell death. As such, 3BP can potentially serve as an anti-tumorigenic agent. Our previous research showed that 3BP can induce...

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Detalles Bibliográficos
Autores principales:	Sun, Yiming, Liu, Zhe, Zou, Xue, Lan, Yadong, Sun, Xiaojin, Wang, Xiu, Zhao, Surong, Jiang, Chenchen, Liu, Hao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546694/ https://www.ncbi.nlm.nih.gov/pubmed/26054380 http://dx.doi.org/10.1007/s10863-015-9612-1

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