The Globular State of the Single-Stranded RNA: Effect of the Secondary Structure Rearrangements

The mutual influence of the slow rearrangements of secondary structure and fast collapse of the long single-stranded RNA (ssRNA) in approximation of coarse-grained model is studied with analytic calculations. It is assumed that the characteristic time of the secondary structure rearrangement is much...

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Detalles Bibliográficos
Autores principales: Grigoryan, Zareh A., Karapetian, Armen T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546806/
https://www.ncbi.nlm.nih.gov/pubmed/26345143
http://dx.doi.org/10.1155/2015/295264
Descripción
Sumario:The mutual influence of the slow rearrangements of secondary structure and fast collapse of the long single-stranded RNA (ssRNA) in approximation of coarse-grained model is studied with analytic calculations. It is assumed that the characteristic time of the secondary structure rearrangement is much longer than that for the formation of the tertiary structure. A nonequilibrium phase transition of the 2nd order has been observed.

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