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Invasion of ovarian cancer cells is induced byPITX2-mediated activation of TGF-β and Activin-A
BACKGROUND: Most ovarian cancers are highly invasive in nature and the high burden of metastatic disease make them a leading cause of mortality among all gynaecological malignancies. The homeodomain transcription factor, PITX2 is associated with cancer in different tissues. Our previous studies demo...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546816/ https://www.ncbi.nlm.nih.gov/pubmed/26298390 http://dx.doi.org/10.1186/s12943-015-0433-y |