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Molecular docking based screening of novel designed chalcone series of compounds for their anti-cancer activity targeting EGFR kinase domain

Epidermal growth factor receptors (EGFR) are critical for the growth of many tumors and expressed at high levels in about one third of epithelial cancers. Hence, blockade of the binding sites for EGFR has been hypothesized as an effective anti-cancer therapy. Chalcone derivative compounds have been...

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Detalles Bibliográficos
Autores principales:	Rao, Chennu Maruthi Malya Prasada, Yejella, Rajendra Prasad, Rehman, Rehman Shaik Abdul, Basha, Syed Hussain
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Biomedical Informatics 2015
Materias:	Hypothesis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546990/ https://www.ncbi.nlm.nih.gov/pubmed/26339147 http://dx.doi.org/10.6026/97320630011322

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