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Interactions of the EGFR juxtamembrane domain with PIP(2)-containing lipid bilayers: Insights from multiscale molecular dynamics simulations()

BACKGROUND: The epidermal growth factor receptor (EGFR) is the best characterised member of the receptor tyrosine kinases, which play an important role in signalling across mammalian cell membranes. The EGFR juxtamembrane (JM) domain is involved in the mechanism of activation of the receptor, intera...

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Detalles Bibliográficos
Autores principales:	Abd Halim, Khairul Bariyyah, Koldsø, Heidi, Sansom, Mark S.P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Pub. Co 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547087/ https://www.ncbi.nlm.nih.gov/pubmed/25219456 http://dx.doi.org/10.1016/j.bbagen.2014.09.006

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