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The Ku subunit of telomerase binds Sir4 to recruit telomerase to lengthen telomeres in S. cerevisiae

In Saccharomyces cerevisiae and in humans, the telomerase RNA subunit is bound by Ku, a ring-shaped protein heterodimer best known for its function in DNA repair. Ku binding to yeast telomerase RNA promotes telomere lengthening and telomerase recruitment to telomeres, but how this is achieved remain...

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Detalles Bibliográficos
Autores principales:	Hass, Evan P, Zappulla, David C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2015
Materias:	Genes and Chromosomes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547093/ https://www.ncbi.nlm.nih.gov/pubmed/26218225 http://dx.doi.org/10.7554/eLife.07750

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