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Use of double-stranded DNA mini-circles to characterize the covalent topoisomerase-DNA complex

The enzymatic DNA relaxation requires the DNA to be transiently nicked and rejoined, the covalent topoisomerase-DNA complex being a key intermediate of the nicking-joining reaction. Practically, this reaction is most often characterized by oligonucleotides. However, the incision-religation of an oli...

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Detalles Bibliográficos
Autores principales:	Millet, Armêl, Strauss, François, Delagoutte, Emmanuelle
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547392/ https://www.ncbi.nlm.nih.gov/pubmed/26300432 http://dx.doi.org/10.1038/srep13154

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