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A Caged Ret Kinase Inhibitor and its Effect on Motoneuron Development in Zebrafish Embryos
Proto-oncogene tyrosine-protein kinase receptor RET is implicated in the development and maintenance of neurons of the central and peripheral nervous systems. Attaching activity-compromising photocleavable groups (caging) to inhibitors could allow for external spatiotemporally controlled inhibition...
Autores principales: | Bliman, David, Nilsson, Jesper R., Kettunen, Petronella, Andréasson, Joakim, Grøtli, Morten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547397/ https://www.ncbi.nlm.nih.gov/pubmed/26300345 http://dx.doi.org/10.1038/srep13109 |
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