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RVD2: an ultra-sensitive variant detection model for low-depth heterogeneous next-generation sequencing data
Motivation: Next-generation sequencing technology is increasingly being used for clinical diagnostic tests. Clinical samples are often genomically heterogeneous due to low sample purity or the presence of genetic subpopulations. Therefore, a variant calling algorithm for calling low-frequency polymo...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547613/ https://www.ncbi.nlm.nih.gov/pubmed/25931517 http://dx.doi.org/10.1093/bioinformatics/btv275 |