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Plasmodium falciparum genetic crosses in a humanized mouse model

Genetic crosses of phenotypically distinct strains of the human malaria parasite Plasmodium falciparum are a powerful tool for identifying genes controlling drug resistance and other key phenotypes. Previous studies relied on the isolation of recombinant parasites from splenectomized chimpanzees, a...

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Detalles Bibliográficos
Autores principales: Vaughan, Ashley M., Pinapati, Richard S., Cheeseman, Ian H., Camargo, Nelly, Fishbaugher, Matthew, Checkley, Lisa A., Nair, Shalini, Hutyra, Carolyn A., Nosten, François H., Anderson, Timothy J. C., Ferdig, Michael T., Kappe, Stefan H. I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547688/
https://www.ncbi.nlm.nih.gov/pubmed/26030447
http://dx.doi.org/10.1038/nmeth.3432