Cargando…

Plasmodium falciparum genetic crosses in a humanized mouse model

Genetic crosses of phenotypically distinct strains of the human malaria parasite Plasmodium falciparum are a powerful tool for identifying genes controlling drug resistance and other key phenotypes. Previous studies relied on the isolation of recombinant parasites from splenectomized chimpanzees, a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vaughan, Ashley M., Pinapati, Richard S., Cheeseman, Ian H., Camargo, Nelly, Fishbaugher, Matthew, Checkley, Lisa A., Nair, Shalini, Hutyra, Carolyn A., Nosten, François H., Anderson, Timothy J. C., Ferdig, Michael T., Kappe, Stefan H. I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547688/ https://www.ncbi.nlm.nih.gov/pubmed/26030447 http://dx.doi.org/10.1038/nmeth.3432

Ejemplares similares

The power and promise of genetic mapping from Plasmodium falciparum crosses utilizing human liver-chimeric mice
por: Button-Simons, Katrina A., et al.
Publicado: (2021)

Pairwise growth competitions identify relative fitness relationships among artemisinin resistant Plasmodium falciparum field isolates
por: Tirrell, Abigail R., et al.
Publicado: (2019)

Genetic mapping of fitness determinants across the malaria parasite Plasmodium falciparum life cycle
por: Li, Xue, et al.
Publicado: (2019)

A Malaria Parasite Cross Reveals Genetic Determinants of Plasmodium falciparum Growth in Different Culture Media
por: Kumar, Sudhir, et al.
Publicado: (2022)

Optimizing bulk segregant analysis of drug resistance using Plasmodium falciparum genetic crosses conducted in humanized mice
por: Brenneman, Katelyn Vendrely, et al.
Publicado: (2022)

A Plasmodium falciparum genetic cross reveals the contributions of pfcrt and plasmepsin II/III to piperaquine drug resistance
por: Kane, John, et al.
Publicado: (2023)

Chloroquine resistance evolution in Plasmodium falciparum is mediated by the putative amino acid transporter AAT1
por: Amambua-Ngwa, Alfred, et al.
Publicado: (2023)

Longitudinal genomic surveillance of Plasmodium falciparum malaria parasites reveals complex genomic architecture of emerging artemisinin resistance
por: Cerqueira, Gustavo C., et al.
Publicado: (2017)

PfCap380 as a marker for Plasmodium falciparum oocyst development in vivo and in vitro
por: Itsara, Leslie S., et al.
Publicado: (2018)

An integrative analysis of small molecule transcriptional responses in the human malaria parasite Plasmodium falciparum
por: Siwo, Geoffrey H., et al.
Publicado: (2015)

An optimized microarray platform for assaying genomic variation in Plasmodium falciparum field populations
por: Tan, John C, et al.
Publicado: (2011)

A Plasmodium falciparum ATP-binding cassette transporter is essential for liver stage entry into schizogony
por: Goswami, Debashree, et al.
Publicado: (2022)

The landscape of inherited and de novo copy number variants in a plasmodium falciparum genetic cross
por: Samarakoon, Upeka, et al.
Publicado: (2011)

Nonlinear Mixed-Effects Modelling of In Vitro Drug Susceptibility and Molecular Correlates of Multidrug Resistant Plasmodium falciparum
por: Simpson, Julie A., et al.
Publicado: (2013)

Predicting functional and regulatory divergence of a drug resistance transporter gene in the human malaria parasite
por: Siwo, Geoffrey H, et al.
Publicado: (2015)

Combating multidrug‐resistant Plasmodium falciparum malaria
por: Thu, Aung Myint, et al.
Publicado: (2017)

Artemisinin-Resistant Plasmodium falciparum K13 Mutant Alleles, Thailand–Myanmar Border
por: Boullé, Mikael, et al.
Publicado: (2016)

Quantification of multiple infections of Plasmodium falciparum in vitro
por: Wacker, Mark A, et al.
Publicado: (2012)

Humoral protection against mosquito bite-transmitted Plasmodium falciparum infection in humanized mice
por: Sack, Brandon K., et al.
Publicado: (2017)

A rapid and scalable density gradient purification method for Plasmodium sporozoites
por: Kennedy, Mark, et al.
Publicado: (2012)

Plasmodium falciparum CRK5 Is Critical for Male Gametogenesis and Infection of the Mosquito
por: Kumar, Sudhir, et al.
Publicado: (2022)

Plasmodium vivax Relapse Rates Following Plasmodium falciparum Malaria Reflect Previous Transmission Intensity
por: Ashley, Elizabeth A, et al.
Publicado: (2019)

Clinically uncomplicated Plasmodium falciparum malaria with high schizontaemia: A case report
por: Lwin, Khin Maung, et al.
Publicado: (2008)

Functional Analysis of Sirtuin Genes in Multiple Plasmodium falciparum Strains
por: Merrick, Catherine J., et al.
Publicado: (2015)

Gene copy number variation throughout the Plasmodium falciparum genome
por: Cheeseman, Ian H, et al.
Publicado: (2009)

Close kinship within multiple-genotype malaria parasite infections
por: Nkhoma, Standwell C., et al.
Publicado: (2012)

A comprehensive model for assessment of liver stage therapies targeting Plasmodium vivax and Plasmodium falciparum
por: Roth, Alison, et al.
Publicado: (2018)

Single-cell genomics for dissection of complex malaria infections
por: Nair, Shalini, et al.
Publicado: (2014)

Metabolic QTL Analysis Links Chloroquine Resistance in Plasmodium falciparum to Impaired Hemoglobin Catabolism
por: Lewis, Ian A., et al.
Publicado: (2014)

Plasmodium falciparum Liver Stage Infection and Transition to Stable Blood Stage Infection in Liver-Humanized and Blood-Humanized FRGN KO Mice Enables Testing of Blood Stage Inhibitory Antibodies (Reticulocyte-Binding Protein Homolog 5) In Vivo
por: Foquet, Lander, et al.
Publicado: (2018)

Plasmodium microtubule-binding protein EB1 is critical for partitioning of nuclei in male gametogenesis
por: Mauer, Sydney, et al.
Publicado: (2023)

Altered expression of K13 disrupts DNA replication and repair in Plasmodium falciparum
por: Gibbons, Justin, et al.
Publicado: (2018)

Graph theoretical approach to study eQTL: a case study of Plasmodium falciparum
por: Huang, Yang, et al.
Publicado: (2009)

Cyclic GMP Balance Is Critical for Malaria Parasite Transmission from the Mosquito to the Mammalian Host
por: Lakshmanan, Viswanathan, et al.
Publicado: (2015)

Global gene expression of human malaria parasite liver stages throughout intrahepatocytic development
por: Zanghi, Gigliola, et al.
Publicado: (2023)

Plasmodium falciparum Calcium-Dependent Protein Kinase 4 is Critical for Male Gametogenesis and Transmission to the Mosquito Vector
por: Kumar, Sudhir, et al.
Publicado: (2021)

Author Correction: A comprehensive model for assessment of liver stage therapies targeting Plasmodium vivax and Plasmodium falciparum
por: Roth, Alison, et al.
Publicado: (2018)

Antibody Responses to Plasmodium falciparum and Plasmodium vivax and Prospective Risk of Plasmodium spp. Infection Postpartum
por: McLean, Alistair R. D., et al.
Publicado: (2017)

Quantitative trait loci mapping reveals candidate pathways regulating cell cycle duration in Plasmodium falciparum
por: Reilly Ayala, Heather B, et al.
Publicado: (2010)

Chemogenomic profiling of Plasmodium falciparum as a tool to aid antimalarial drug discovery
por: Pradhan, Anupam, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_jn59u36aq2v5eflfea2l3jkgpd