Single-Cell Genetic Analysis Using Automated Microfluidics to Resolve Somatic Mosaicism

Somatic mosaicism occurs throughout normal development and contributes to numerous disease etiologies, including tumorigenesis and neurological disorders. Intratumor genetic heterogeneity is inherent to many cancers, creating challenges for effective treatments. Unfortunately, analysis of bulk DNA m...

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Detalles Bibliográficos
Autores principales: Szulwach, Keith E., Chen, Peilin, Wang, Xiaohui, Wang, Jing, Weaver, Lesley S., Gonzales, Michael L., Sun, Gang, Unger, Marc A., Ramakrishnan, Ramesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547741/
https://www.ncbi.nlm.nih.gov/pubmed/26302375
http://dx.doi.org/10.1371/journal.pone.0135007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547741/
https://www.ncbi.nlm.nih.gov/pubmed/26302375
http://dx.doi.org/10.1371/journal.pone.0135007

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