HLA Class-II Associated HIV Polymorphisms Predict Escape from CD4+ T Cell Responses

Antiretroviral therapy, antibody and CD8(+) T cell-mediated responses targeting human immunodeficiency virus-1 (HIV-1) exert selection pressure on the virus necessitating escape; however, the ability of CD4(+) T cells to exert selective pressure remains unclear. Using a computational approach on HIV...

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Detalles Bibliográficos
Autores principales: Erdmann, Nathan, Du, Victor Y., Carlson, Jonathan, Schaefer, Malinda, Jureka, Alexander, Sterrett, Sarah, Yue, Ling, Dilernia, Dario, Lakhi, Shabir, Tang, Jianming, Sidney, John, Gilmour, Jill, Allen, Susan, Hunter, Eric, Heath, Sonya, Bansal, Anju, Goepfert, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547780/
https://www.ncbi.nlm.nih.gov/pubmed/26302050
http://dx.doi.org/10.1371/journal.ppat.1005111

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