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The development of precision medicine in clinical practice
Precision medicine allows a dramatic expansion of biological data, while there is still an urgent need to understand and insight the exact meaning of those data to human health and disease. This has led to an increasing wealth of data unanalyzed. The concept of precision medicine is about the custom...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547974/ https://www.ncbi.nlm.nih.gov/pubmed/26302883 http://dx.doi.org/10.1186/s40169-015-0069-y |
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author | He, Mingyan Xia, Jinglin Shehab, Mohamed Wang, Xiangdong |
author_facet | He, Mingyan Xia, Jinglin Shehab, Mohamed Wang, Xiangdong |
author_sort | He, Mingyan |
collection | PubMed |
description | Precision medicine allows a dramatic expansion of biological data, while there is still an urgent need to understand and insight the exact meaning of those data to human health and disease. This has led to an increasing wealth of data unanalyzed. The concept of precision medicine is about the customization of healthcare, with decisions and practices tailored to an individual patient based on their intrinsic biology in addition to clinical “signs and symptoms”. Construction of a standardized model for the integration of data from various platforms is the central mission of the ‘New Disease Management Model’. The model is helpful for the development of new taxonomy of diseases and subtypes, to personalize therapy based on patient genetic profiles. A rapid progression of precision therapy has been made recently. Clinical trials have shown the therapeutic efficacy of discovered and developed therapeutic agents has improved. However, next-generation drugs would be designed for disease subtypes with more specificity, efficacy and lower toxicity. |
format | Online Article Text |
id | pubmed-4547974 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-45479742015-08-28 The development of precision medicine in clinical practice He, Mingyan Xia, Jinglin Shehab, Mohamed Wang, Xiangdong Clin Transl Med Editorial Precision medicine allows a dramatic expansion of biological data, while there is still an urgent need to understand and insight the exact meaning of those data to human health and disease. This has led to an increasing wealth of data unanalyzed. The concept of precision medicine is about the customization of healthcare, with decisions and practices tailored to an individual patient based on their intrinsic biology in addition to clinical “signs and symptoms”. Construction of a standardized model for the integration of data from various platforms is the central mission of the ‘New Disease Management Model’. The model is helpful for the development of new taxonomy of diseases and subtypes, to personalize therapy based on patient genetic profiles. A rapid progression of precision therapy has been made recently. Clinical trials have shown the therapeutic efficacy of discovered and developed therapeutic agents has improved. However, next-generation drugs would be designed for disease subtypes with more specificity, efficacy and lower toxicity. Springer Berlin Heidelberg 2015-08-25 /pmc/articles/PMC4547974/ /pubmed/26302883 http://dx.doi.org/10.1186/s40169-015-0069-y Text en © He et al. 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Editorial He, Mingyan Xia, Jinglin Shehab, Mohamed Wang, Xiangdong The development of precision medicine in clinical practice |
title | The development of precision medicine in clinical practice |
title_full | The development of precision medicine in clinical practice |
title_fullStr | The development of precision medicine in clinical practice |
title_full_unstemmed | The development of precision medicine in clinical practice |
title_short | The development of precision medicine in clinical practice |
title_sort | development of precision medicine in clinical practice |
topic | Editorial |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547974/ https://www.ncbi.nlm.nih.gov/pubmed/26302883 http://dx.doi.org/10.1186/s40169-015-0069-y |
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