Neuropathic Pain due to Small Fiber Neuropathy in Aging: Current Management and Future Prospects

Over the last 10 years, the diagnosis small fiber neuropathy (SFN) has gained recognition worldwide. Patients often suffer from severe neuropathic pain that may be difficult to treat. A substantial subset of patients with SFN is aged 65 years or older, and these patients often exhibit comorbidities...

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Autores principales: Brouwer, Brigitte A., de Greef, Bianca T. A., Hoeijmakers, Janneke G. J., Geerts, Margot, van Kleef, Maarten, Merkies, Ingemar S. J., Faber, Catharina G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548010/
https://www.ncbi.nlm.nih.gov/pubmed/26239827
http://dx.doi.org/10.1007/s40266-015-0283-8
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author Brouwer, Brigitte A.
de Greef, Bianca T. A.
Hoeijmakers, Janneke G. J.
Geerts, Margot
van Kleef, Maarten
Merkies, Ingemar S. J.
Faber, Catharina G.
author_facet Brouwer, Brigitte A.
de Greef, Bianca T. A.
Hoeijmakers, Janneke G. J.
Geerts, Margot
van Kleef, Maarten
Merkies, Ingemar S. J.
Faber, Catharina G.
author_sort Brouwer, Brigitte A.
collection PubMed
description Over the last 10 years, the diagnosis small fiber neuropathy (SFN) has gained recognition worldwide. Patients often suffer from severe neuropathic pain that may be difficult to treat. A substantial subset of patients with SFN is aged 65 years or older, and these patients often exhibit comorbidities and usage of multiple drugs, making neuropathic pain treatment more challenging. In this review, we highlight relevant pathophysiological aspects and discuss currently used therapeutic strategies for neuropathic pain. Possible pitfalls in neuropathic pain treatment in the elderly will be underlined.
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spelling pubmed-45480102015-08-28 Neuropathic Pain due to Small Fiber Neuropathy in Aging: Current Management and Future Prospects Brouwer, Brigitte A. de Greef, Bianca T. A. Hoeijmakers, Janneke G. J. Geerts, Margot van Kleef, Maarten Merkies, Ingemar S. J. Faber, Catharina G. Drugs Aging Review Article Over the last 10 years, the diagnosis small fiber neuropathy (SFN) has gained recognition worldwide. Patients often suffer from severe neuropathic pain that may be difficult to treat. A substantial subset of patients with SFN is aged 65 years or older, and these patients often exhibit comorbidities and usage of multiple drugs, making neuropathic pain treatment more challenging. In this review, we highlight relevant pathophysiological aspects and discuss currently used therapeutic strategies for neuropathic pain. Possible pitfalls in neuropathic pain treatment in the elderly will be underlined. Springer International Publishing 2015-08-04 2015 /pmc/articles/PMC4548010/ /pubmed/26239827 http://dx.doi.org/10.1007/s40266-015-0283-8 Text en © The Author(s) 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Review Article
Brouwer, Brigitte A.
de Greef, Bianca T. A.
Hoeijmakers, Janneke G. J.
Geerts, Margot
van Kleef, Maarten
Merkies, Ingemar S. J.
Faber, Catharina G.
Neuropathic Pain due to Small Fiber Neuropathy in Aging: Current Management and Future Prospects
title Neuropathic Pain due to Small Fiber Neuropathy in Aging: Current Management and Future Prospects
title_full Neuropathic Pain due to Small Fiber Neuropathy in Aging: Current Management and Future Prospects
title_fullStr Neuropathic Pain due to Small Fiber Neuropathy in Aging: Current Management and Future Prospects
title_full_unstemmed Neuropathic Pain due to Small Fiber Neuropathy in Aging: Current Management and Future Prospects
title_short Neuropathic Pain due to Small Fiber Neuropathy in Aging: Current Management and Future Prospects
title_sort neuropathic pain due to small fiber neuropathy in aging: current management and future prospects
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548010/
https://www.ncbi.nlm.nih.gov/pubmed/26239827
http://dx.doi.org/10.1007/s40266-015-0283-8
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