Cargando…

Clinical effects of sevoflurane anesthesia induction with a portable inhalational anesthetic circuit in pediatric patients

INTRODUCTION: Pediatric anesthesia induction with sevoflurane usually needs a special vaporizer and gas source, which limits its use to the operating room (OR). Many children feel anxious and cry when entering the OR because of being separated from their parents, which impairs anesthesia safety and...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Min, Han, Chuanbao, Zhou, Qinhai, Liu, Cunming, Ding, Zhengnian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548026/
https://www.ncbi.nlm.nih.gov/pubmed/26322092
http://dx.doi.org/10.5114/aoms.2015.50230
_version_ 1782387137747877888
author Yu, Min
Han, Chuanbao
Zhou, Qinhai
Liu, Cunming
Ding, Zhengnian
author_facet Yu, Min
Han, Chuanbao
Zhou, Qinhai
Liu, Cunming
Ding, Zhengnian
author_sort Yu, Min
collection PubMed
description INTRODUCTION: Pediatric anesthesia induction with sevoflurane usually needs a special vaporizer and gas source, which limits its use to the operating room (OR). Many children feel anxious and cry when entering the OR because of being separated from their parents, which impairs anesthesia safety and their physical and mental health. In this study, we used a portable circuit to perform sevoflurane anesthesia induction outside the OR, assessed its effects and compared them with those of ketamine anesthesia in pediatric patients. MATERIAL AND METHODS: One hundred children had anesthesia induced with either sevoflurane (sevoflurane group) through the portable inhalational anesthetic circuit, or ketamine by intramuscular injection (ketamine group), then were transferred to the OR. Peak inspired concentration (Cp) and steady state concentration (Cs) of sevoflurane were measured. Heart rate (HR) and saturation of peripheral oxygen (SpO(2)) were monitored. Time for anesthesia induction, awakening, leaving the OR and duration of the operation were recorded. The patients’ reaction during anesthesia was also analyzed. RESULTS: The Cp and Cs of sevoflurane were correlated with bodyweight. Compared with the ketamine group, the sevoflurane group showed shorter time for anesthesia induction (28 ±7 s vs. 195 ±34 s, p < 0.0001), awakening (11.2 ±3.6 s vs. 63.5 ±6.7 s, p < 0.0001) and leaving the OR (20.5 ±5.6 s vs. 43.4 ±10.6, p < 0.0001), less noncooperation during anesthesia induction (10% vs. 80%, p < 0.0001), lower HR (130 ±16 beats/min vs. 143 ±19 beats/min, p = 0.0004) and higher SpO(2) (98.9 ±0.9% vs. 96.1 ±2.5%, p < 0.0001) on arrival at the OR. CONCLUSIONS: Pediatric anesthesia induction by sevoflurane with the portable inhalational anesthetic circuit is convenient, safe and effective outside the OR.
format Online
Article
Text
id pubmed-4548026
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Termedia Publishing House
record_format MEDLINE/PubMed
spelling pubmed-45480262015-08-28 Clinical effects of sevoflurane anesthesia induction with a portable inhalational anesthetic circuit in pediatric patients Yu, Min Han, Chuanbao Zhou, Qinhai Liu, Cunming Ding, Zhengnian Arch Med Sci Clinical Research INTRODUCTION: Pediatric anesthesia induction with sevoflurane usually needs a special vaporizer and gas source, which limits its use to the operating room (OR). Many children feel anxious and cry when entering the OR because of being separated from their parents, which impairs anesthesia safety and their physical and mental health. In this study, we used a portable circuit to perform sevoflurane anesthesia induction outside the OR, assessed its effects and compared them with those of ketamine anesthesia in pediatric patients. MATERIAL AND METHODS: One hundred children had anesthesia induced with either sevoflurane (sevoflurane group) through the portable inhalational anesthetic circuit, or ketamine by intramuscular injection (ketamine group), then were transferred to the OR. Peak inspired concentration (Cp) and steady state concentration (Cs) of sevoflurane were measured. Heart rate (HR) and saturation of peripheral oxygen (SpO(2)) were monitored. Time for anesthesia induction, awakening, leaving the OR and duration of the operation were recorded. The patients’ reaction during anesthesia was also analyzed. RESULTS: The Cp and Cs of sevoflurane were correlated with bodyweight. Compared with the ketamine group, the sevoflurane group showed shorter time for anesthesia induction (28 ±7 s vs. 195 ±34 s, p < 0.0001), awakening (11.2 ±3.6 s vs. 63.5 ±6.7 s, p < 0.0001) and leaving the OR (20.5 ±5.6 s vs. 43.4 ±10.6, p < 0.0001), less noncooperation during anesthesia induction (10% vs. 80%, p < 0.0001), lower HR (130 ±16 beats/min vs. 143 ±19 beats/min, p = 0.0004) and higher SpO(2) (98.9 ±0.9% vs. 96.1 ±2.5%, p < 0.0001) on arrival at the OR. CONCLUSIONS: Pediatric anesthesia induction by sevoflurane with the portable inhalational anesthetic circuit is convenient, safe and effective outside the OR. Termedia Publishing House 2015-03-26 2015-08-12 /pmc/articles/PMC4548026/ /pubmed/26322092 http://dx.doi.org/10.5114/aoms.2015.50230 Text en Copyright © 2015 Termedia & Banach http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial 3.0 Unported License, permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Research
Yu, Min
Han, Chuanbao
Zhou, Qinhai
Liu, Cunming
Ding, Zhengnian
Clinical effects of sevoflurane anesthesia induction with a portable inhalational anesthetic circuit in pediatric patients
title Clinical effects of sevoflurane anesthesia induction with a portable inhalational anesthetic circuit in pediatric patients
title_full Clinical effects of sevoflurane anesthesia induction with a portable inhalational anesthetic circuit in pediatric patients
title_fullStr Clinical effects of sevoflurane anesthesia induction with a portable inhalational anesthetic circuit in pediatric patients
title_full_unstemmed Clinical effects of sevoflurane anesthesia induction with a portable inhalational anesthetic circuit in pediatric patients
title_short Clinical effects of sevoflurane anesthesia induction with a portable inhalational anesthetic circuit in pediatric patients
title_sort clinical effects of sevoflurane anesthesia induction with a portable inhalational anesthetic circuit in pediatric patients
topic Clinical Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548026/
https://www.ncbi.nlm.nih.gov/pubmed/26322092
http://dx.doi.org/10.5114/aoms.2015.50230
work_keys_str_mv AT yumin clinicaleffectsofsevofluraneanesthesiainductionwithaportableinhalationalanestheticcircuitinpediatricpatients
AT hanchuanbao clinicaleffectsofsevofluraneanesthesiainductionwithaportableinhalationalanestheticcircuitinpediatricpatients
AT zhouqinhai clinicaleffectsofsevofluraneanesthesiainductionwithaportableinhalationalanestheticcircuitinpediatricpatients
AT liucunming clinicaleffectsofsevofluraneanesthesiainductionwithaportableinhalationalanestheticcircuitinpediatricpatients
AT dingzhengnian clinicaleffectsofsevofluraneanesthesiainductionwithaportableinhalationalanestheticcircuitinpediatricpatients