Cargando…
Echocardiographic assessment of right ventricular function in responders and non-responders to cardiac resynchronization therapy
INTRODUCTION: The aim of this study was to determine whether baseline right ventricular (RV) function assessed by standard echocardiography may indicate patients who will respond to cardiac resynchronization therapy (CRT). MATERIAL AND METHODS: The data of 57 patients (54 men, 95%), aged 66.4 ±8.7 y...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Termedia Publishing House
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548031/ https://www.ncbi.nlm.nih.gov/pubmed/26322084 http://dx.doi.org/10.5114/aoms.2015.53292 |
_version_ | 1782387138901311488 |
---|---|
author | Kusiak, Aleksander Wiliński, Jerzy Wojciechowska, Wiktoria Jastrzębski, Marek Sondej, Tomasz Kloch-Badełek, Małgorzata Czarnecka, Danuta M. |
author_facet | Kusiak, Aleksander Wiliński, Jerzy Wojciechowska, Wiktoria Jastrzębski, Marek Sondej, Tomasz Kloch-Badełek, Małgorzata Czarnecka, Danuta M. |
author_sort | Kusiak, Aleksander |
collection | PubMed |
description | INTRODUCTION: The aim of this study was to determine whether baseline right ventricular (RV) function assessed by standard echocardiography may indicate patients who will respond to cardiac resynchronization therapy (CRT). MATERIAL AND METHODS: The data of 57 patients (54 men, 95%), aged 66.4 ±8.7 years with heart failure (HF) having a CRT device implanted were collected. All patients had left ventricular ejection fraction (LVEF) ≤ 35% and QRS complex duration ≥ 120 ms. Echocardiographic examination with tissue Doppler imaging techniques and complex RV evaluation were performed at baseline and three months after CRT onset. RESULTS: Three months after CRT implantation, patients responding to CRT, defined as a reduction of left ventricle end-systolic volume (LVESV) of at least 10% (n = 34), compared to patients with a reduction of LVESV of less than 10% (n = 23), had at baseline a smaller right atrium diameter (47.85 ±11.33 mm vs. 52.65 ±8.69 mm; p = 0.028), higher TAPSE (14.56 ±2.57 mm vs. 13.04 ±2.93 mm; p = 0.030) and lower grade of tricuspid valve regurgitation (1.82 ±0.97 vs. 2.3 ±0.88; p = 0.033). CONCLUSIONS: This study showed that there are differences in baseline right ventricular function between responders and non-responders to CRT. Yet in our study, none of the baseline RV parameters provided any value in identifying patients who would respond to CRT. |
format | Online Article Text |
id | pubmed-4548031 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Termedia Publishing House |
record_format | MEDLINE/PubMed |
spelling | pubmed-45480312015-08-28 Echocardiographic assessment of right ventricular function in responders and non-responders to cardiac resynchronization therapy Kusiak, Aleksander Wiliński, Jerzy Wojciechowska, Wiktoria Jastrzębski, Marek Sondej, Tomasz Kloch-Badełek, Małgorzata Czarnecka, Danuta M. Arch Med Sci Clinical Research INTRODUCTION: The aim of this study was to determine whether baseline right ventricular (RV) function assessed by standard echocardiography may indicate patients who will respond to cardiac resynchronization therapy (CRT). MATERIAL AND METHODS: The data of 57 patients (54 men, 95%), aged 66.4 ±8.7 years with heart failure (HF) having a CRT device implanted were collected. All patients had left ventricular ejection fraction (LVEF) ≤ 35% and QRS complex duration ≥ 120 ms. Echocardiographic examination with tissue Doppler imaging techniques and complex RV evaluation were performed at baseline and three months after CRT onset. RESULTS: Three months after CRT implantation, patients responding to CRT, defined as a reduction of left ventricle end-systolic volume (LVESV) of at least 10% (n = 34), compared to patients with a reduction of LVESV of less than 10% (n = 23), had at baseline a smaller right atrium diameter (47.85 ±11.33 mm vs. 52.65 ±8.69 mm; p = 0.028), higher TAPSE (14.56 ±2.57 mm vs. 13.04 ±2.93 mm; p = 0.030) and lower grade of tricuspid valve regurgitation (1.82 ±0.97 vs. 2.3 ±0.88; p = 0.033). CONCLUSIONS: This study showed that there are differences in baseline right ventricular function between responders and non-responders to CRT. Yet in our study, none of the baseline RV parameters provided any value in identifying patients who would respond to CRT. Termedia Publishing House 2015-08-11 2015-08-12 /pmc/articles/PMC4548031/ /pubmed/26322084 http://dx.doi.org/10.5114/aoms.2015.53292 Text en Copyright © 2015 Termedia & Banach http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial 3.0 Unported License, permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Clinical Research Kusiak, Aleksander Wiliński, Jerzy Wojciechowska, Wiktoria Jastrzębski, Marek Sondej, Tomasz Kloch-Badełek, Małgorzata Czarnecka, Danuta M. Echocardiographic assessment of right ventricular function in responders and non-responders to cardiac resynchronization therapy |
title | Echocardiographic assessment of right ventricular function in responders and non-responders to cardiac resynchronization therapy |
title_full | Echocardiographic assessment of right ventricular function in responders and non-responders to cardiac resynchronization therapy |
title_fullStr | Echocardiographic assessment of right ventricular function in responders and non-responders to cardiac resynchronization therapy |
title_full_unstemmed | Echocardiographic assessment of right ventricular function in responders and non-responders to cardiac resynchronization therapy |
title_short | Echocardiographic assessment of right ventricular function in responders and non-responders to cardiac resynchronization therapy |
title_sort | echocardiographic assessment of right ventricular function in responders and non-responders to cardiac resynchronization therapy |
topic | Clinical Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548031/ https://www.ncbi.nlm.nih.gov/pubmed/26322084 http://dx.doi.org/10.5114/aoms.2015.53292 |
work_keys_str_mv | AT kusiakaleksander echocardiographicassessmentofrightventricularfunctioninrespondersandnonresponderstocardiacresynchronizationtherapy AT wilinskijerzy echocardiographicassessmentofrightventricularfunctioninrespondersandnonresponderstocardiacresynchronizationtherapy AT wojciechowskawiktoria echocardiographicassessmentofrightventricularfunctioninrespondersandnonresponderstocardiacresynchronizationtherapy AT jastrzebskimarek echocardiographicassessmentofrightventricularfunctioninrespondersandnonresponderstocardiacresynchronizationtherapy AT sondejtomasz echocardiographicassessmentofrightventricularfunctioninrespondersandnonresponderstocardiacresynchronizationtherapy AT klochbadełekmałgorzata echocardiographicassessmentofrightventricularfunctioninrespondersandnonresponderstocardiacresynchronizationtherapy AT czarneckadanutam echocardiographicassessmentofrightventricularfunctioninrespondersandnonresponderstocardiacresynchronizationtherapy |