Expanding opportunities for mining bioactive chemistry from patents

Bioactive structures published in medicinal chemistry patents typically exceed those in papers by at least twofold and may precede them by several years. The Big-Bang of open automated extraction since 2012 has contributed to over 15 million patent-derived compounds in PubChem. While mapping between...

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Detalles Bibliográficos
Autor principal: Southan, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
From Chemistry to Biology Database Curation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548146/
https://www.ncbi.nlm.nih.gov/pubmed/26194581
http://dx.doi.org/10.1016/j.ddtec.2014.12.001
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author Southan, Christopher
author_facet Southan, Christopher
author_sort Southan, Christopher
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description Bioactive structures published in medicinal chemistry patents typically exceed those in papers by at least twofold and may precede them by several years. The Big-Bang of open automated extraction since 2012 has contributed to over 15 million patent-derived compounds in PubChem. While mapping between chemical structures, assay results and protein targets from patent documents is challenging, these relationships can be harvested using open tools and are beginning to be curated into databases.
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spelling pubmed-45481462015-09-03 Expanding opportunities for mining bioactive chemistry from patents Southan, Christopher Drug Discov Today Technol From Chemistry to Biology Database Curation Bioactive structures published in medicinal chemistry patents typically exceed those in papers by at least twofold and may precede them by several years. The Big-Bang of open automated extraction since 2012 has contributed to over 15 million patent-derived compounds in PubChem. While mapping between chemical structures, assay results and protein targets from patent documents is challenging, these relationships can be harvested using open tools and are beginning to be curated into databases. Elsevier 2015-02-10 /pmc/articles/PMC4548146/ /pubmed/26194581 http://dx.doi.org/10.1016/j.ddtec.2014.12.001 Text en © 2015 The Author https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle From Chemistry to Biology Database Curation
Southan, Christopher
Expanding opportunities for mining bioactive chemistry from patents
title Expanding opportunities for mining bioactive chemistry from patents
title_full Expanding opportunities for mining bioactive chemistry from patents
title_fullStr Expanding opportunities for mining bioactive chemistry from patents
title_full_unstemmed Expanding opportunities for mining bioactive chemistry from patents
title_short Expanding opportunities for mining bioactive chemistry from patents
title_sort expanding opportunities for mining bioactive chemistry from patents
topic From Chemistry to Biology Database Curation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548146/
https://www.ncbi.nlm.nih.gov/pubmed/26194581
http://dx.doi.org/10.1016/j.ddtec.2014.12.001
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