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Exposure of Monocytes to Lipoarabinomannan Promotes Their Differentiation into Functionally and Phenotypically Immature Macrophages

Lipoarabinomannan (LAM) is a lipid virulence factor secreted by Mycobacterium tuberculosis (Mtb), the etiologic agent of tuberculosis. LAM can be measured in the urine or serum of tuberculosis patients (TB-patients). Circulating monocytes are the precursor cells of alveolar macrophages and might be...

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Detalles Bibliográficos
Autores principales: Chávez-Galán, Leslie, Ocaña-Guzmán, Ranferi, Torre-Bouscoulet, Luis, García-de-Alba, Carolina, Sada-Ovalle, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548148/
https://www.ncbi.nlm.nih.gov/pubmed/26347897
http://dx.doi.org/10.1155/2015/984973