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Gene expression parallels synaptic excitability and plasticity changes in Alzheimer’s disease
Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by abnormal accumulation of β-amyloid and tau and synapse dysfunction in memory-related neural circuits. Pathological and functional changes in the medial temporal lobe, a region essential for explicit memory encoding, contribute...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548151/ https://www.ncbi.nlm.nih.gov/pubmed/26379494 http://dx.doi.org/10.3389/fncel.2015.00318 |