Cargando…

LGR4 and Its Role in Intestinal Protection and Energy Metabolism

Leucine-rich repeat-containing G protein-coupled receptors were identified by the unique nature of their long leucine-rich repeat extracellular domains. Distinct from classical G protein-coupled receptors which act via G proteins, LGR4 functions mainly through Wnt/β-catenin signaling to regulate cel...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Ziru, Zhang, Weizhen, Mulholland, Michael W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548225/ https://www.ncbi.nlm.nih.gov/pubmed/26379625 http://dx.doi.org/10.3389/fendo.2015.00131

Ejemplares similares

LGR4, a G Protein-Coupled Receptor With a Systemic Role: From Development to Metabolic Regulation
por: Filipowska, Joanna, et al.
Publicado: (2022)

Emerging Roles for LGR4 in Organ Development, Energy Metabolism and Carcinogenesis
por: Yang, Linlin, et al.
Publicado: (2022)

LGR4 Gene Polymorphisms Are Associated With Bone and Obesity Phenotypes in Chinese Female Nuclear Families
por: Shi, Su-qin, et al.
Publicado: (2021)

Adipose Tissue Remodeling: Its Role in Energy Metabolism and Metabolic Disorders
por: Choe, Sung Sik, et al.
Publicado: (2016)

In a Class of Their Own – RXFP1 and RXFP2 are Unique Members of the LGR Family
por: Petrie, Emma J., et al.
Publicado: (2015)

Genes Encoding the Glycoprotein Hormone GPA2/GPB5 and the Receptor LGR1 in a Female Prawn
por: Wahl, Melody, et al.
Publicado: (2022)

LGR4 and LGR5 Function Redundantly During Human Endoderm Differentiation
por: Tsai, Yu-Hwai, et al.
Publicado: (2016)

Role of Intestinal Bitter Sensing in Enteroendocrine Hormone Secretion and Metabolic Control
por: Xie, Cong, et al.
Publicado: (2018)

Multiple roles and regulatory mechanisms of the transcription factor HNF4 in the intestine
por: Vemuri, Kiranmayi, et al.
Publicado: (2023)

Role of Energy Metabolism in the Brown Fat Gene Program
por: Nam, Minwoo, et al.
Publicado: (2015)

The Role of Osteoclast Energy Metabolism in the Occurrence and Development of Osteoporosis
por: Da, Wacili, et al.
Publicado: (2021)

LGR4: A New Receptor Member in Endocrine and Metabolic Diseases
por: Zhang, Ningning, et al.
Publicado: (2023)

A Naturally Occurring Lgr4 Splice Variant Encodes a Soluble Antagonist Useful for Demonstrating the Gonadal Roles of Lgr4 in Mammals
por: Hsu, Pei-Jen, et al.
Publicado: (2014)

Pleiotrophin and metabolic disorders: insights into its role in metabolism
por: Ballesteros-Pla, Cristina, et al.
Publicado: (2023)

Lgr4 in Ocular Development and Glaucoma
por: Siwko, Stefan, et al.
Publicado: (2013)

Monolayer culture of intestinal epithelium sustains Lgr5(+) intestinal stem cells
por: Liu, Yuan, et al.
Publicado: (2018)

Lgr5(+) intestinal stem cell sorting and organoid culture
por: Liu, Ruixue, et al.
Publicado: (2019)

Emerging role of substance and energy metabolism associated with neuroendocrine regulation in tumor cells
por: Liu, Yingying, et al.
Publicado: (2023)

The Role of LGR4 (GPR48) in Normal and Cancer Processes
por: Ordaz-Ramos, Alejandro, et al.
Publicado: (2021)

The Role of Melanin-Concentrating Hormone and Its Receptors in Energy Homeostasis
por: MacNeil, Douglas J.
Publicado: (2013)

Depletion of Myostatin b Promotes Somatic Growth and Lipid Metabolism in Zebrafish
por: Gao, Yanping, et al.
Publicado: (2016)

Corrigendum: Depletion of Myostatin b Promotes Somatic Growth and Lipid Metabolism in Zebrafish
por: Gao, Yanping, et al.
Publicado: (2019)

Heterogeneity of the Level of Activity of Lgr5+ Intestinal Stem Cells
por: Moossavi, Shirin
Publicado: (2014)

Role of Innate lymphoid Cells in Obesity and Insulin Resistance
por: Chen, Hong, et al.
Publicado: (2022)

The Roles of Mitochondrial SIRT4 in Cellular Metabolism
por: Min, Zheying, et al.
Publicado: (2019)

LGR4 and LGR5 form distinct homodimers that only LGR4 complexes with RNF43/ZNRF3 to provide high affinity binding of R-spondin ligands
por: Toh, Yukimatsu, et al.
Publicado: (2023)

Editorial: Mitochondrial Biology and Its Role in Metabolic Diseases
por: Schneider, Jochen G., et al.
Publicado: (2022)

Emerging role for leucine-rich repeat-containing G-protein-coupled receptors LGR5 and LGR4 in cancer stem cells
por: Nakata, Susumu, et al.
Publicado: (2014)

Nesfatin-1 promotes brown adipocyte phenotype
por: Wang, Yuexin, et al.
Publicado: (2016)

LGR4 and LGR5 Regulate Hair Cell Differentiation in the Sensory Epithelium of the Developing Mouse Cochlea
por: Żak, Magdalena, et al.
Publicado: (2016)

Profiles and diagnostic value of intestinal microbiota in schizophrenia patients with metabolic syndrome
por: Xing, Mengjuan, et al.
Publicado: (2023)

R-Spondin Potentiates Wnt/β-Catenin Signaling through Orphan Receptors LGR4 and LGR5
por: Ruffner, Heinz, et al.
Publicado: (2012)

LGR4 is required for sequential molar development
por: Yamakami, Yukiko, et al.
Publicado: (2016)

Lgr5+ telocytes are a signaling source at the intestinal villus tip
por: Bahar Halpern, Keren, et al.
Publicado: (2020)

LGR5 and LGR6 in stem cell biology and ovarian cancer
por: Schindler, Adam J., et al.
Publicado: (2017)

LGR5 Activates Noncanonical Wnt Signaling and Inhibits Aldosterone Production in the Human Adrenal
por: Shaikh, Lalarukh Haris, et al.
Publicado: (2015)

The Role of the Intestinal Microbiota in Nonalcoholic Steatohepatitis
por: Xiang, Hui, et al.
Publicado: (2022)

Impaired Intestinal Barrier and Tissue Bacteria: Pathomechanisms for Metabolic Diseases
por: Massier, Lucas, et al.
Publicado: (2021)

Lower ghrelin levels does not impact the metabolic benefit induced by Roux-en-Y gastric bypass
por: Liang, Yuan, et al.
Publicado: (2022)

Phase Two Steroid Metabolism and Its Roles in Breast and Prostate Cancer Patients
por: McNamara, Keely M., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_jlpc94jgp4afjalo4o0tcr7oj1