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Structure-based design of novel naproxen derivatives targeting monomeric nucleoprotein of Influenza A virus

The nucleoprotein (NP) binds the viral RNA genome as oligomers assembled with the polymerase in a ribonucleoprotein complex required for transcription and replication of influenza A virus. Novel antiviral candidates targeting the nucleoprotein either induced higher order oligomers or reduced NP olig...

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Detalles Bibliográficos
Autores principales:	Tarus, Bogdan, Bertrand, Hélène, Zedda, Gloria, Di Primo, Carmelo, Quideau, Stéphane, Slama-Schwok, Anny
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548311/ https://www.ncbi.nlm.nih.gov/pubmed/25333630 http://dx.doi.org/10.1080/07391102.2014.979230

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