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Translational challenges of animal models in Chagas disease drug development: a review
Chagas disease, or American trypanosomiasis, caused by Trypanosoma cruzi parasite infection is endemic in Latin America and presents an increasing clinical challenge due to migrating populations. Despite being first identified over a century ago, only two drugs are available for its treatment, and r...
Autores principales: | Chatelain, Eric, Konar, Nandini |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548737/ https://www.ncbi.nlm.nih.gov/pubmed/26316715 http://dx.doi.org/10.2147/DDDT.S90208 |
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