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Migraine in menopausal women: a systematic review
Evidence suggests that migraine activity is influenced by hormonal factors, and particularly by estrogen levels, but relatively few studies have investigated the prevalence and characteristics of migraine according to the menopausal status. Overall, population-based studies have shown an improvement...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548761/ https://www.ncbi.nlm.nih.gov/pubmed/26316824 http://dx.doi.org/10.2147/IJWH.S70073 |
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author | Ripa, Patrizia Ornello, Raffaele Degan, Diana Tiseo, Cindy Stewart, Janet Pistoia, Francesca Carolei, Antonio Sacco, Simona |
author_facet | Ripa, Patrizia Ornello, Raffaele Degan, Diana Tiseo, Cindy Stewart, Janet Pistoia, Francesca Carolei, Antonio Sacco, Simona |
author_sort | Ripa, Patrizia |
collection | PubMed |
description | Evidence suggests that migraine activity is influenced by hormonal factors, and particularly by estrogen levels, but relatively few studies have investigated the prevalence and characteristics of migraine according to the menopausal status. Overall, population-based studies have shown an improvement of migraine after menopause, with a possible increase in perimenopause. On the contrary, the studies performed on patients referring to headache centers have shown no improvement or even worsening of migraine. Menopause etiology may play a role in migraine evolution during the menopausal period, with migraine improvement more likely occurring after spontaneous rather than after surgical menopause. Postmenopausal hormone replacement therapy has been found to be associated with migraine worsening in observational population-based studies. The effects of several therapeutic regimens on migraine has also been investigated, leading to nonconclusive results. To date, no specific preventive measures are recommended for menopausal women with migraine. There is a need for further research in order to clarify the relationship between migraine and hormonal changes in women, and to quantify the real burden of migraine after the menopause. Hormonal manipulation for the treatment of refractory postmenopausal migraine is still a matter of debate. |
format | Online Article Text |
id | pubmed-4548761 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-45487612015-08-27 Migraine in menopausal women: a systematic review Ripa, Patrizia Ornello, Raffaele Degan, Diana Tiseo, Cindy Stewart, Janet Pistoia, Francesca Carolei, Antonio Sacco, Simona Int J Womens Health Review Evidence suggests that migraine activity is influenced by hormonal factors, and particularly by estrogen levels, but relatively few studies have investigated the prevalence and characteristics of migraine according to the menopausal status. Overall, population-based studies have shown an improvement of migraine after menopause, with a possible increase in perimenopause. On the contrary, the studies performed on patients referring to headache centers have shown no improvement or even worsening of migraine. Menopause etiology may play a role in migraine evolution during the menopausal period, with migraine improvement more likely occurring after spontaneous rather than after surgical menopause. Postmenopausal hormone replacement therapy has been found to be associated with migraine worsening in observational population-based studies. The effects of several therapeutic regimens on migraine has also been investigated, leading to nonconclusive results. To date, no specific preventive measures are recommended for menopausal women with migraine. There is a need for further research in order to clarify the relationship between migraine and hormonal changes in women, and to quantify the real burden of migraine after the menopause. Hormonal manipulation for the treatment of refractory postmenopausal migraine is still a matter of debate. Dove Medical Press 2015-08-20 /pmc/articles/PMC4548761/ /pubmed/26316824 http://dx.doi.org/10.2147/IJWH.S70073 Text en © 2015 Ripa et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. |
spellingShingle | Review Ripa, Patrizia Ornello, Raffaele Degan, Diana Tiseo, Cindy Stewart, Janet Pistoia, Francesca Carolei, Antonio Sacco, Simona Migraine in menopausal women: a systematic review |
title | Migraine in menopausal women: a systematic review |
title_full | Migraine in menopausal women: a systematic review |
title_fullStr | Migraine in menopausal women: a systematic review |
title_full_unstemmed | Migraine in menopausal women: a systematic review |
title_short | Migraine in menopausal women: a systematic review |
title_sort | migraine in menopausal women: a systematic review |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548761/ https://www.ncbi.nlm.nih.gov/pubmed/26316824 http://dx.doi.org/10.2147/IJWH.S70073 |
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