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TRPV1 channel inhibition contributes to the antinociceptive effects of Croton macrostachyus extract in mice

BACKGROUND: Previous study showed that extracts from Croton macrostachyus (Euphorbiaceae) exhibit analgesic effects in acute pain models. The present study evaluates the antinociceptive properties of the methanol/methylene chloride extract (MECM) of the stem bark of this plant using mice models of p...

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Detalles Bibliográficos
Autores principales: Nguelefack, Télesphore Benoît, Dutra, Rafael Cypriano, Paszcuk, Ana Flavia, de Andrade, Edinéia Lemos, Calixto, João Batista
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548910/
https://www.ncbi.nlm.nih.gov/pubmed/26303910
http://dx.doi.org/10.1186/s12906-015-0816-z