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Evidence for Retromutagenesis as a Mechanism for Adaptive Mutation in Escherichia coli
Adaptive mutation refers to the continuous outgrowth of new mutants from a non-dividing cell population during selection, in apparent violation of the neo-Darwinian principle that mutation precedes selection. One explanation is that of retromutagenesis, in which a DNA lesion causes a transcriptional...
Autores principales: | Morreall, Jordan, Kim, Alice, Liu, Yuan, Degtyareva, Natalya, Weiss, Bernard, Doetsch, Paul W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548950/ https://www.ncbi.nlm.nih.gov/pubmed/26305558 http://dx.doi.org/10.1371/journal.pgen.1005477 |
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