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Epidemiological and virological characteristics of influenza B: results of the Global Influenza B Study
INTRODUCTION: Literature on influenza focuses on influenza A, despite influenza B having a large public health impact. The Global Influenza B Study aims to collect information on global epidemiology and burden of disease of influenza B since 2000. METHODS: Twenty-six countries in the Southern (n = 5...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549097/ https://www.ncbi.nlm.nih.gov/pubmed/26256290 http://dx.doi.org/10.1111/irv.12319 |
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author | Caini, Saverio Huang, Q Sue Ciblak, Meral A Kusznierz, Gabriela Owen, Rhonda Wangchuk, Sonam Henriques, Cláudio M P Njouom, Richard Fasce, Rodrigo A Yu, Hongjie Feng, Luzhao Zambon, Maria Clara, Alexey W Kosasih, Herman Puzelli, Simona Kadjo, Herve A Emukule, Gideon Heraud, Jean-Michel Ang, Li Wei Venter, Marietjie Mironenko, Alla Brammer, Lynnette Mai, Le Thi Quynh Schellevis, François Plotkin, Stanley Paget, John |
author_facet | Caini, Saverio Huang, Q Sue Ciblak, Meral A Kusznierz, Gabriela Owen, Rhonda Wangchuk, Sonam Henriques, Cláudio M P Njouom, Richard Fasce, Rodrigo A Yu, Hongjie Feng, Luzhao Zambon, Maria Clara, Alexey W Kosasih, Herman Puzelli, Simona Kadjo, Herve A Emukule, Gideon Heraud, Jean-Michel Ang, Li Wei Venter, Marietjie Mironenko, Alla Brammer, Lynnette Mai, Le Thi Quynh Schellevis, François Plotkin, Stanley Paget, John |
author_sort | Caini, Saverio |
collection | PubMed |
description | INTRODUCTION: Literature on influenza focuses on influenza A, despite influenza B having a large public health impact. The Global Influenza B Study aims to collect information on global epidemiology and burden of disease of influenza B since 2000. METHODS: Twenty-six countries in the Southern (n = 5) and Northern (n = 7) hemispheres and intertropical belt (n = 14) provided virological and epidemiological data. We calculated the proportion of influenza cases due to type B and Victoria and Yamagata lineages in each country and season; tested the correlation between proportion of influenza B and maximum weekly influenza-like illness (ILI) rate during the same season; determined the frequency of vaccine mismatches; and described the age distribution of cases by virus type. RESULTS: The database included 935 673 influenza cases (2000–2013). Overall median proportion of influenza B was 22·6%, with no statistically significant differences across seasons. During seasons where influenza B was dominant or co-circulated (>20% of total detections), Victoria and Yamagata lineages predominated during 64% and 36% of seasons, respectively, and a vaccine mismatch was observed in ≈25% of seasons. Proportion of influenza B was inversely correlated with maximum ILI rate in the same season in the Northern and (with borderline significance) Southern hemispheres. Patients infected with influenza B were usually younger (5–17 years) than patients infected with influenza A. CONCLUSION: Influenza B is a common disease with some epidemiological differences from influenza A. This should be considered when optimizing control/prevention strategies in different regions and reducing the global burden of disease due to influenza. |
format | Online Article Text |
id | pubmed-4549097 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | John Wiley & Sons, Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-45490972015-08-28 Epidemiological and virological characteristics of influenza B: results of the Global Influenza B Study Caini, Saverio Huang, Q Sue Ciblak, Meral A Kusznierz, Gabriela Owen, Rhonda Wangchuk, Sonam Henriques, Cláudio M P Njouom, Richard Fasce, Rodrigo A Yu, Hongjie Feng, Luzhao Zambon, Maria Clara, Alexey W Kosasih, Herman Puzelli, Simona Kadjo, Herve A Emukule, Gideon Heraud, Jean-Michel Ang, Li Wei Venter, Marietjie Mironenko, Alla Brammer, Lynnette Mai, Le Thi Quynh Schellevis, François Plotkin, Stanley Paget, John Influenza Other Respir Viruses Original Articles INTRODUCTION: Literature on influenza focuses on influenza A, despite influenza B having a large public health impact. The Global Influenza B Study aims to collect information on global epidemiology and burden of disease of influenza B since 2000. METHODS: Twenty-six countries in the Southern (n = 5) and Northern (n = 7) hemispheres and intertropical belt (n = 14) provided virological and epidemiological data. We calculated the proportion of influenza cases due to type B and Victoria and Yamagata lineages in each country and season; tested the correlation between proportion of influenza B and maximum weekly influenza-like illness (ILI) rate during the same season; determined the frequency of vaccine mismatches; and described the age distribution of cases by virus type. RESULTS: The database included 935 673 influenza cases (2000–2013). Overall median proportion of influenza B was 22·6%, with no statistically significant differences across seasons. During seasons where influenza B was dominant or co-circulated (>20% of total detections), Victoria and Yamagata lineages predominated during 64% and 36% of seasons, respectively, and a vaccine mismatch was observed in ≈25% of seasons. Proportion of influenza B was inversely correlated with maximum ILI rate in the same season in the Northern and (with borderline significance) Southern hemispheres. Patients infected with influenza B were usually younger (5–17 years) than patients infected with influenza A. CONCLUSION: Influenza B is a common disease with some epidemiological differences from influenza A. This should be considered when optimizing control/prevention strategies in different regions and reducing the global burden of disease due to influenza. John Wiley & Sons, Ltd 2015-08 2015-08-10 /pmc/articles/PMC4549097/ /pubmed/26256290 http://dx.doi.org/10.1111/irv.12319 Text en Copyright © 2015 John Wiley & Sons Ltd http://creativecommons.org/licenses/by-nc/4.0/ This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Original Articles Caini, Saverio Huang, Q Sue Ciblak, Meral A Kusznierz, Gabriela Owen, Rhonda Wangchuk, Sonam Henriques, Cláudio M P Njouom, Richard Fasce, Rodrigo A Yu, Hongjie Feng, Luzhao Zambon, Maria Clara, Alexey W Kosasih, Herman Puzelli, Simona Kadjo, Herve A Emukule, Gideon Heraud, Jean-Michel Ang, Li Wei Venter, Marietjie Mironenko, Alla Brammer, Lynnette Mai, Le Thi Quynh Schellevis, François Plotkin, Stanley Paget, John Epidemiological and virological characteristics of influenza B: results of the Global Influenza B Study |
title | Epidemiological and virological characteristics of influenza B: results of the Global Influenza B Study |
title_full | Epidemiological and virological characteristics of influenza B: results of the Global Influenza B Study |
title_fullStr | Epidemiological and virological characteristics of influenza B: results of the Global Influenza B Study |
title_full_unstemmed | Epidemiological and virological characteristics of influenza B: results of the Global Influenza B Study |
title_short | Epidemiological and virological characteristics of influenza B: results of the Global Influenza B Study |
title_sort | epidemiological and virological characteristics of influenza b: results of the global influenza b study |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549097/ https://www.ncbi.nlm.nih.gov/pubmed/26256290 http://dx.doi.org/10.1111/irv.12319 |
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