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Epidemiological and virological characteristics of influenza B: results of the Global Influenza B Study

INTRODUCTION: Literature on influenza focuses on influenza A, despite influenza B having a large public health impact. The Global Influenza B Study aims to collect information on global epidemiology and burden of disease of influenza B since 2000. METHODS: Twenty-six countries in the Southern (n = 5...

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Autores principales: Caini, Saverio, Huang, Q Sue, Ciblak, Meral A, Kusznierz, Gabriela, Owen, Rhonda, Wangchuk, Sonam, Henriques, Cláudio M P, Njouom, Richard, Fasce, Rodrigo A, Yu, Hongjie, Feng, Luzhao, Zambon, Maria, Clara, Alexey W, Kosasih, Herman, Puzelli, Simona, Kadjo, Herve A, Emukule, Gideon, Heraud, Jean-Michel, Ang, Li Wei, Venter, Marietjie, Mironenko, Alla, Brammer, Lynnette, Mai, Le Thi Quynh, Schellevis, François, Plotkin, Stanley, Paget, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549097/
https://www.ncbi.nlm.nih.gov/pubmed/26256290
http://dx.doi.org/10.1111/irv.12319
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author Caini, Saverio
Huang, Q Sue
Ciblak, Meral A
Kusznierz, Gabriela
Owen, Rhonda
Wangchuk, Sonam
Henriques, Cláudio M P
Njouom, Richard
Fasce, Rodrigo A
Yu, Hongjie
Feng, Luzhao
Zambon, Maria
Clara, Alexey W
Kosasih, Herman
Puzelli, Simona
Kadjo, Herve A
Emukule, Gideon
Heraud, Jean-Michel
Ang, Li Wei
Venter, Marietjie
Mironenko, Alla
Brammer, Lynnette
Mai, Le Thi Quynh
Schellevis, François
Plotkin, Stanley
Paget, John
author_facet Caini, Saverio
Huang, Q Sue
Ciblak, Meral A
Kusznierz, Gabriela
Owen, Rhonda
Wangchuk, Sonam
Henriques, Cláudio M P
Njouom, Richard
Fasce, Rodrigo A
Yu, Hongjie
Feng, Luzhao
Zambon, Maria
Clara, Alexey W
Kosasih, Herman
Puzelli, Simona
Kadjo, Herve A
Emukule, Gideon
Heraud, Jean-Michel
Ang, Li Wei
Venter, Marietjie
Mironenko, Alla
Brammer, Lynnette
Mai, Le Thi Quynh
Schellevis, François
Plotkin, Stanley
Paget, John
author_sort Caini, Saverio
collection PubMed
description INTRODUCTION: Literature on influenza focuses on influenza A, despite influenza B having a large public health impact. The Global Influenza B Study aims to collect information on global epidemiology and burden of disease of influenza B since 2000. METHODS: Twenty-six countries in the Southern (n = 5) and Northern (n = 7) hemispheres and intertropical belt (n = 14) provided virological and epidemiological data. We calculated the proportion of influenza cases due to type B and Victoria and Yamagata lineages in each country and season; tested the correlation between proportion of influenza B and maximum weekly influenza-like illness (ILI) rate during the same season; determined the frequency of vaccine mismatches; and described the age distribution of cases by virus type. RESULTS: The database included 935 673 influenza cases (2000–2013). Overall median proportion of influenza B was 22·6%, with no statistically significant differences across seasons. During seasons where influenza B was dominant or co-circulated (>20% of total detections), Victoria and Yamagata lineages predominated during 64% and 36% of seasons, respectively, and a vaccine mismatch was observed in ≈25% of seasons. Proportion of influenza B was inversely correlated with maximum ILI rate in the same season in the Northern and (with borderline significance) Southern hemispheres. Patients infected with influenza B were usually younger (5–17 years) than patients infected with influenza A. CONCLUSION: Influenza B is a common disease with some epidemiological differences from influenza A. This should be considered when optimizing control/prevention strategies in different regions and reducing the global burden of disease due to influenza.
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spelling pubmed-45490972015-08-28 Epidemiological and virological characteristics of influenza B: results of the Global Influenza B Study Caini, Saverio Huang, Q Sue Ciblak, Meral A Kusznierz, Gabriela Owen, Rhonda Wangchuk, Sonam Henriques, Cláudio M P Njouom, Richard Fasce, Rodrigo A Yu, Hongjie Feng, Luzhao Zambon, Maria Clara, Alexey W Kosasih, Herman Puzelli, Simona Kadjo, Herve A Emukule, Gideon Heraud, Jean-Michel Ang, Li Wei Venter, Marietjie Mironenko, Alla Brammer, Lynnette Mai, Le Thi Quynh Schellevis, François Plotkin, Stanley Paget, John Influenza Other Respir Viruses Original Articles INTRODUCTION: Literature on influenza focuses on influenza A, despite influenza B having a large public health impact. The Global Influenza B Study aims to collect information on global epidemiology and burden of disease of influenza B since 2000. METHODS: Twenty-six countries in the Southern (n = 5) and Northern (n = 7) hemispheres and intertropical belt (n = 14) provided virological and epidemiological data. We calculated the proportion of influenza cases due to type B and Victoria and Yamagata lineages in each country and season; tested the correlation between proportion of influenza B and maximum weekly influenza-like illness (ILI) rate during the same season; determined the frequency of vaccine mismatches; and described the age distribution of cases by virus type. RESULTS: The database included 935 673 influenza cases (2000–2013). Overall median proportion of influenza B was 22·6%, with no statistically significant differences across seasons. During seasons where influenza B was dominant or co-circulated (>20% of total detections), Victoria and Yamagata lineages predominated during 64% and 36% of seasons, respectively, and a vaccine mismatch was observed in ≈25% of seasons. Proportion of influenza B was inversely correlated with maximum ILI rate in the same season in the Northern and (with borderline significance) Southern hemispheres. Patients infected with influenza B were usually younger (5–17 years) than patients infected with influenza A. CONCLUSION: Influenza B is a common disease with some epidemiological differences from influenza A. This should be considered when optimizing control/prevention strategies in different regions and reducing the global burden of disease due to influenza. John Wiley & Sons, Ltd 2015-08 2015-08-10 /pmc/articles/PMC4549097/ /pubmed/26256290 http://dx.doi.org/10.1111/irv.12319 Text en Copyright © 2015 John Wiley & Sons Ltd http://creativecommons.org/licenses/by-nc/4.0/ This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Original Articles
Caini, Saverio
Huang, Q Sue
Ciblak, Meral A
Kusznierz, Gabriela
Owen, Rhonda
Wangchuk, Sonam
Henriques, Cláudio M P
Njouom, Richard
Fasce, Rodrigo A
Yu, Hongjie
Feng, Luzhao
Zambon, Maria
Clara, Alexey W
Kosasih, Herman
Puzelli, Simona
Kadjo, Herve A
Emukule, Gideon
Heraud, Jean-Michel
Ang, Li Wei
Venter, Marietjie
Mironenko, Alla
Brammer, Lynnette
Mai, Le Thi Quynh
Schellevis, François
Plotkin, Stanley
Paget, John
Epidemiological and virological characteristics of influenza B: results of the Global Influenza B Study
title Epidemiological and virological characteristics of influenza B: results of the Global Influenza B Study
title_full Epidemiological and virological characteristics of influenza B: results of the Global Influenza B Study
title_fullStr Epidemiological and virological characteristics of influenza B: results of the Global Influenza B Study
title_full_unstemmed Epidemiological and virological characteristics of influenza B: results of the Global Influenza B Study
title_short Epidemiological and virological characteristics of influenza B: results of the Global Influenza B Study
title_sort epidemiological and virological characteristics of influenza b: results of the global influenza b study
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549097/
https://www.ncbi.nlm.nih.gov/pubmed/26256290
http://dx.doi.org/10.1111/irv.12319
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