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Mutations in the DI-DII Linker of Human Parainfluenza Virus Type 3 Fusion Protein Result in Diminished Fusion Activity
Human parainfluenza virus type 3 (HPIV3) can cause severe respiratory tract diseases in infants and young children, but no licensed vaccines or antiviral agents are currently available for treatment. Fusing the viral and target cell membranes is a prerequisite for its entry into host cells and is di...
Autores principales: | Xie, Wenyan, Wen, Hongling, Chu, Fulu, Yan, Shaofeng, Lin, Bin, Xie, Wenli, Liu, Ying, Ren, Guijie, Zhao, Li, Song, Yanyan, Sun, Chengxi, Wang, Zhiyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549179/ https://www.ncbi.nlm.nih.gov/pubmed/26305905 http://dx.doi.org/10.1371/journal.pone.0136474 |
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