Cyclooxygenase-2 and Prostaglandin E(2) Signaling through Prostaglandin Receptor EP-2 Favor the Development of Myocarditis during Acute Trypanosoma cruzi Infection

Inflammation plays an important role in the pathophysiology of Chagas disease, caused by Trypanosoma cruzi. Prostanoids are regulators of homeostasis and inflammation and are produced mainly by myeloid cells, being cyclooxygenases, COX-1 and COX-2, the key enzymes in their biosynthesis from arachido...

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Detalles Bibliográficos
Autores principales: Guerrero, Néstor A., Camacho, Mercedes, Vila, Luis, Íñiguez, Miguel A., Chillón-Marinas, Carlos, Cuervo, Henar, Poveda, Cristina, Fresno, Manuel, Gironès, Núria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549243/
https://www.ncbi.nlm.nih.gov/pubmed/26305786
http://dx.doi.org/10.1371/journal.pntd.0004025

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