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NDR Kinases Are Essential for Somitogenesis and Cardiac Looping during Mouse Embryonic Development
Studies of mammalian tissue culture cells indicate that the conserved and distinct NDR isoforms, NDR1 and NDR2, play essential cell biological roles. However, mice lacking either Ndr1 or Ndr2 alone develop normally. Here, we studied the physiological consequences of inactivating both NDR1 and NDR2 i...
Autores principales: | Schmitz-Rohmer, Debora, Probst, Simone, Yang, Zhong-Zhou, Laurent, Frédéric, Stadler, Michael B., Zuniga, Aimée, Zeller, Rolf, Hynx, Debby, Hemmings, Brian A., Hergovich, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549247/ https://www.ncbi.nlm.nih.gov/pubmed/26305214 http://dx.doi.org/10.1371/journal.pone.0136566 |
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