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The UVB-Stimulated Expression of Transglutaminase 1 Is Mediated Predominantly via the NFκB Signaling Pathway: New Evidence of Its Significant Attenuation through the Specific Interruption of the p38/MSK1/NFκBp65 Ser276 Axis

The influence of ultraviolet B (UVB) radiation on transglutaminase 1 (TGase 1), a major factor that regulates skin keratinization, has not been sufficiently characterized especially at the gene or protein level. Thus, we determined whether UVB affects the expression of TGase 1 in human keratinocytes...

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Detalles Bibliográficos
Autores principales: Terazawa, Shuko, Mori, Shingo, Nakajima, Hiroaki, Yasuda, Michitaka, Imokawa, Genji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549294/
https://www.ncbi.nlm.nih.gov/pubmed/26305102
http://dx.doi.org/10.1371/journal.pone.0136311