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Direct Renin Inhibition with Aliskiren Improves Ischemia-Induced Neovasculogenesis in Diabetic Animals via the SDF-1 Related Mechanism
OBJECTIVE: Aliskiren is a direct renin inhibitor which is suggested to modify proangiogenic cells in addition to lower blood pressure. Given that angiogenesis is impaired in the presence of diabetes mellitus, we would like to investigate whether and how aliskiren enhances endothelial progenitor cell...
Autores principales: | Chang, Ting-Ting, Wu, Tao-Cheng, Huang, Po-Hsun, Lin, Chih-Pei, Chen, Jia-Shiong, Lin, Liang-Yu, Lin, Shing-Jong, Chen, Jaw-Wen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549314/ https://www.ncbi.nlm.nih.gov/pubmed/26305217 http://dx.doi.org/10.1371/journal.pone.0136627 |
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