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Iatrogenic Cushing syndrome and adrenal insufficiency during concomitant therapy with ritonavir and fluticasone

Ritonavir is a potent inhibitor of the cytochrome P450 enzyme CYP3A4 and is subject to multiple drug–drug interactions. This becomes especially important when the patient is also taking medications metabolized through CYP3A pathway as increased and potentially toxic drug levels may ensue. Herein we...

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Detalles Bibliográficos
Autores principales: Epperla, Narendranath, McKiernan, Fergus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549367/
https://www.ncbi.nlm.nih.gov/pubmed/26322261
http://dx.doi.org/10.1186/s40064-015-1218-x

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