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Inhibition of human GLUT1 and GLUT5 by plant carbohydrate products; insights into transport specificity

Glucose transporters GLUT1 (transports glucose) and GLUT5 (transports fructose), in addition to their functions in normal metabolism, have been implicated in several diseases including cancer and diabetes. While GLUT1 has several inhibitors, none have been described for GLUT5. By transport activity...

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Detalles Bibliográficos
Autores principales: George Thompson, Alayna M., Iancu, Cristina V., Nguyen, Thi Thanh Hanh, Kim, Doman, Choe, Jun-yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549712/
https://www.ncbi.nlm.nih.gov/pubmed/26306809
http://dx.doi.org/10.1038/srep12804

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