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Inhibition of human GLUT1 and GLUT5 by plant carbohydrate products; insights into transport specificity
Glucose transporters GLUT1 (transports glucose) and GLUT5 (transports fructose), in addition to their functions in normal metabolism, have been implicated in several diseases including cancer and diabetes. While GLUT1 has several inhibitors, none have been described for GLUT5. By transport activity...
Autores principales: | George Thompson, Alayna M., Iancu, Cristina V., Nguyen, Thi Thanh Hanh, Kim, Doman, Choe, Jun-yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549712/ https://www.ncbi.nlm.nih.gov/pubmed/26306809 http://dx.doi.org/10.1038/srep12804 |
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