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Increased expression of the interleukin-1 receptor-associated kinase (IRAK)-1 is associated with adipose tissue inflammatory state in obesity

BACKGROUND: The emerging role of TLR2/4 as immuno-metabolic receptors points to key involvement of TLR/IL-1R/MyD88 pathway in obesity/type-2 diabetes (T2D). IL1R-associated kinase (IRAK)-1 is a critical adapter protein (serine/threonine kinase) of this signaling pathway. The changes in adipose tissu...

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Detalles Bibliográficos
Autores principales:	Ahmad, Rasheed, Shihab, Puthiyaveetil Kochumon, Thomas, Reeby, Alghanim, Munera, Hasan, Amal, Sindhu, Sardar, Behbehani, Kazem
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549832/ https://www.ncbi.nlm.nih.gov/pubmed/26312071 http://dx.doi.org/10.1186/s13098-015-0067-7

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