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In silico design and analysis of a new hyperglycosylated analog of erythropoietin to improve drug efficacy

BACKGROUND: The enhancement of glycosylation by applying glycoengineering approaches has become widely used to boost properties for protein therapeutics. The objective of this work was to engineer a new hyperglycosylated analog of erythropoietin (EPO) with appropriately targeted N-linked carbohydrat...

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Detalles Bibliográficos
Autores principales:	Kianmehr, Anvarsadat, Mohammadi, Hamid Shahbaz, Shokrgozar, Mohammad Ali, Omidinia, Eskandar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Medknow Publications & Media Pvt Ltd 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549927/ https://www.ncbi.nlm.nih.gov/pubmed/26322290 http://dx.doi.org/10.4103/2277-9175.161548

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