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The transcription factor ERG increases expression of neurotransmitter receptors on prostate cancer cells

BACKGROUND: The TMPRSS2-ERG gene fusion occurs in about half of prostate cancer (PCa) cases and results in overexpression of the transcription factor ERG. Overexpression of ERG has many effects on cellular function. However, how these changes enhance cell growth and promote tumor development is uncl...

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Detalles Bibliográficos
Autores principales: Kissick, Haydn T., On, Seung T., Dunn, Laura K., Sanda, Martin G., Asara, John M., Pellegrini, Kathryn L., Noel, Jonathan K., Arredouani, Mohamed S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549934/
https://www.ncbi.nlm.nih.gov/pubmed/26310325
http://dx.doi.org/10.1186/s12885-015-1612-3