Ultrahigh field MRI in clinical neuroimmunology: a potential contribution to improved diagnostics and personalised disease management

Conventional magnetic resonance imaging (MRI) at 1.5 Tesla (T) is limited by modest spatial resolution and signal-to-noise ratio (SNR), impeding the identification and classification of inflammatory central nervous system changes in current clinical practice. Gaining from enhanced susceptibility eff...

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Autores principales: Sinnecker, Tim, Kuchling, Joseph, Dusek, Petr, Dörr, Jan, Niendorf, Thoralf, Paul, Friedemann, Wuerfel, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549950/
https://www.ncbi.nlm.nih.gov/pubmed/26312125
http://dx.doi.org/10.1186/s13167-015-0038-y
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author Sinnecker, Tim
Kuchling, Joseph
Dusek, Petr
Dörr, Jan
Niendorf, Thoralf
Paul, Friedemann
Wuerfel, Jens
author_facet Sinnecker, Tim
Kuchling, Joseph
Dusek, Petr
Dörr, Jan
Niendorf, Thoralf
Paul, Friedemann
Wuerfel, Jens
author_sort Sinnecker, Tim
collection PubMed
description Conventional magnetic resonance imaging (MRI) at 1.5 Tesla (T) is limited by modest spatial resolution and signal-to-noise ratio (SNR), impeding the identification and classification of inflammatory central nervous system changes in current clinical practice. Gaining from enhanced susceptibility effects and improved SNR, ultrahigh field MRI at 7 T depicts inflammatory brain lesions in great detail. This review summarises recent reports on 7 T MRI in neuroinflammatory diseases and addresses the question as to whether ultrahigh field MRI may eventually improve clinical decision-making and personalised disease management.
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spelling pubmed-45499502015-08-27 Ultrahigh field MRI in clinical neuroimmunology: a potential contribution to improved diagnostics and personalised disease management Sinnecker, Tim Kuchling, Joseph Dusek, Petr Dörr, Jan Niendorf, Thoralf Paul, Friedemann Wuerfel, Jens EPMA J Review Conventional magnetic resonance imaging (MRI) at 1.5 Tesla (T) is limited by modest spatial resolution and signal-to-noise ratio (SNR), impeding the identification and classification of inflammatory central nervous system changes in current clinical practice. Gaining from enhanced susceptibility effects and improved SNR, ultrahigh field MRI at 7 T depicts inflammatory brain lesions in great detail. This review summarises recent reports on 7 T MRI in neuroinflammatory diseases and addresses the question as to whether ultrahigh field MRI may eventually improve clinical decision-making and personalised disease management. BioMed Central 2015-08-27 /pmc/articles/PMC4549950/ /pubmed/26312125 http://dx.doi.org/10.1186/s13167-015-0038-y Text en © Sinnecker et al. 2015 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0 (http://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Sinnecker, Tim
Kuchling, Joseph
Dusek, Petr
Dörr, Jan
Niendorf, Thoralf
Paul, Friedemann
Wuerfel, Jens
Ultrahigh field MRI in clinical neuroimmunology: a potential contribution to improved diagnostics and personalised disease management
title Ultrahigh field MRI in clinical neuroimmunology: a potential contribution to improved diagnostics and personalised disease management
title_full Ultrahigh field MRI in clinical neuroimmunology: a potential contribution to improved diagnostics and personalised disease management
title_fullStr Ultrahigh field MRI in clinical neuroimmunology: a potential contribution to improved diagnostics and personalised disease management
title_full_unstemmed Ultrahigh field MRI in clinical neuroimmunology: a potential contribution to improved diagnostics and personalised disease management
title_short Ultrahigh field MRI in clinical neuroimmunology: a potential contribution to improved diagnostics and personalised disease management
title_sort ultrahigh field mri in clinical neuroimmunology: a potential contribution to improved diagnostics and personalised disease management
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549950/
https://www.ncbi.nlm.nih.gov/pubmed/26312125
http://dx.doi.org/10.1186/s13167-015-0038-y
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