Caspase-7: a critical mediator of optic nerve injury-induced retinal ganglion cell death

BACKGROUND: Axonal injury of the optic nerve (ON) is involved in various ocular diseases, such as glaucoma and traumatic optic neuropathy, which leads to apoptotic death of retinal ganglion cells (RGCs) and loss of vision. Caspases have been implicated in RGC pathogenesis. However, the role of caspa...

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Detalles Bibliográficos
Autores principales: Choudhury, Shreyasi, Liu, Yang, Clark, Abbot F., Pang, Iok-Hou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550044/
https://www.ncbi.nlm.nih.gov/pubmed/26306916
http://dx.doi.org/10.1186/s13024-015-0039-2

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