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A physical association between the human mutY homolog (hMYH) and DNA topoisomerase II-binding protein 1 (hTopBP1) regulates Chk1-induced cell cycle arrest in HEK293 cells

BACKGROUND: Human DNA topoisomerase II-binding protein 1 (hTopBP1) plays an important role in DNA replication and the DNA damage checkpoint pathway. The human mutY homolog (hMYH) is a base excision repair DNA glycosylase that excises adenines or 2-hydroxyadenines that are mispaired with guanine or 7...

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Detalles Bibliográficos
Autores principales:	Han, Se Hee, Hahm, Soo-Hyun, Tran, An Hue Vy, Chung, Ji Hyung, Hong, Myoung-Ki, Paik, Hyun-Dong, Kim, Key-Sun, Han, Ye Sun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550056/ https://www.ncbi.nlm.nih.gov/pubmed/26312135 http://dx.doi.org/10.1186/s13578-015-0042-x

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