Biology-Driven Gene-Gene Interaction Analysis of Age-Related Cataract in the eMERGE Network

Bioinformatics approaches to examine gene-gene models provide a means to discover interactions between multiple genes that underlie complex disease. Extensive computational demands and adjusting for multiple testing make uncovering genetic interactions a challenge. Here, we address these issues usin...

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Detalles Bibliográficos
Autores principales: Hall, Molly A, Verma, Shefali S, Wallace, John, Lucas, Anastasia, Berg, Richard L, Connolly, John, Crawford, Dana C, Crosslin, David R, de Andrade, Mariza, Doheny, Kimberly F, Haines, Jonathan L, Harley, John B, Jarvik, Gail P, Kitchner, Terrie, Kuivaniemi, Helena, Larson, Eric B, Carrell, David S, Tromp, Gerard, Vrabec, Tamara R, Pendergrass, Sarah A, McCarty, Catherine A, Ritchie, Marylyn D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550090/
https://www.ncbi.nlm.nih.gov/pubmed/25982363
http://dx.doi.org/10.1002/gepi.21902

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