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LytB1 and LytB2 of Mycobacterium tuberculosis Are Not Genetically Redundant

Mycobacterium tuberculosis synthesises isoprenoid precursors via the MEP/DOXP pathway and at least five enzymes in the pathway (Dxs1, Dxr/IspC, IspD, IspF, and GcpE/IspG) are required for growth in vitro. We investigated the role of LytB (IspH) in M. tuberculosis; M. tuberculosis is unusual in that...

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Detalles Bibliográficos
Autores principales:	Brown, Amanda Claire, Kokoczka, Rachel, Parish, Tanya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550268/ https://www.ncbi.nlm.nih.gov/pubmed/26309039 http://dx.doi.org/10.1371/journal.pone.0135638

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