Overexpression of Both ERG11 and ABC2 Genes Might Be Responsible for Itraconazole Resistance in Clinical Isolates of Candida krusei

OBJECTIVE: To study the main molecular mechanisms responsible for itraconazole resistance in clinical isolates of Candida krusei. METHODS: The 14α-demethylases encoded by ERG11 gene in the 16 C.krusei clinical isolates were amplified by polymerase chain reaction (PCR), and their nucleotide sequences...

Descripción completa

Detalles Bibliográficos
Autores principales: He, Xiaoyuan, Zhao, Mingfeng, Chen, Jinyan, Wu, Rimao, Zhang, Jianlei, Cui, Rui, Jiang, Yanyu, Chen, Jie, Cao, Xiaoli, Xing, Yi, Zhang, Yuchen, Meng, Juanxia, Deng, Qi, Sui, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550294/
https://www.ncbi.nlm.nih.gov/pubmed/26308936
http://dx.doi.org/10.1371/journal.pone.0136185

Ejemplares similares

Ejemplares similares